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TAKE CONTROL OF HEMOPHILIA B

With Rebinyn®, you get more ways to take control—with simple dosing, flexible storage, and fast infusions.

Leopoldo lives with hemophilia B and is sailing

All images of hemophilia B patients shown are for illustrative purposes only.

All images of hemophilia B patients shown are for illustrative purposes only.

SIMPLIFIED FACTOR IX DOSING.

Sticky note: The recommended Rebinyn® dose for all patients is 40 IU/kg for minor or moderate bleeds, or 80 IU/kg for major bleeds

The recommended dose for all patients is 40 IU/kg for minor or moderate bleeds, or 80 IU/kg for major bleeds.a

  • Follow your health care provider’s instructions regarding the dose and schedule for infusing Rebinyn®
  • Do not attempt to do an infusion yourself unless you have been taught how by your health care provider or hemophilia treatment center 

aA single dose should be enough for minor and moderate bleeds. Your doctor may recommend additional doses of 40 IU/kg.

WITH FLEXIBLE STORAGE, REBINYN® MAY FIT YOUR LIFESTYLE.

Rebinyn® does not require refrigeration—so you can bring it with you when you’re on the go. Flexible storage means Rebinyn® can be stored at up to 86˚F, and it’s room temperature stable for up to 6 months, or up to 4 hours post-reconstitution. 

bIf you choose to store Rebinyn® at room temperature, do not return it to the refrigerator. Rebinyn® vials can also be stored in the refrigerator at 36ºF-46ºF for up to 24 months until the expiration date stated on the label. Please see Prescribing Information for complete storage instructions.

QUICK TO PREPARE AND FAST TO INFUSE

If your time is important to you, then we have good news: Rebinyn® can be infused in as little as 1-4 minutes. And with our prefilled syringe, preparing a dose is quick, too.

With MixPro®, preparing a dose of Rebinyn® is as quick as:

Attachc

Prefilled diluent syringe contains 4 mL of diluent—works with any dose strength

Twistc

Adapter connects the syringe and vial

Mixc

After mixing, you can infuse Rebinyn®

cFor complete instructions on reconstitution and use, please refer to the Instructions for Use.

KEEPING TRACK IS QUICK, TOO

3 different Rebinyn® vials with peel-off labels

Each vial comes with a peel-off label, which may help you track details about your infusions.

Rebinyn® can be infused in 1-4 minutes
Preparing Rebinyn® infusion schema

IT'S EASY TO GET STARTED

We'll show you step-by-step how to start treating with Rebinyn®.

Sticky note with the word

Let's Go

DO YOU PLAN ON TRAVELING?

With a Rebinyn® Travel Case, your factor will be ready when you are.

Rebinyn® Travel Case

Get Yours Today

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Selected Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.
     

Indications and Usage

What is Rebinyn® Coagulation Factor IX (Recombinant), GlycoPEGylated?
Rebinyn® is an injectable medicine used to replace clotting Factor IX that is missing in patients with hemophilia B. Rebinyn® is used to treat and control bleeding in people with hemophilia B. Your healthcare provider may give you Rebinyn® when you have surgery. Rebinyn® is not used for routine prophylaxis or for immune tolerance therapy.
 

Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.

What should I tell my healthcare provider before using Rebinyn®?
Tell your healthcare provider if you:

  • have or have had any medical conditions.
  • take any medicines, including non-prescription medicines and dietary supplements.
  • are nursing, pregnant, or plan to become pregnant.
  • have been told you have inhibitors to Factor IX.

How should I use Rebinyn®?

  • Rebinyn® is given as an infusion into the vein.
  • Call your healthcare provider right away if your bleeding does not stop after taking Rebinyn®.
  • Do not stop using Rebinyn® without consulting your healthcare provider.

What are the possible side effects of Rebinyn®?

  • Common side effects include swelling, pain, rash or redness at the location of the infusion, and itching.
  • Call your healthcare provider right away or get emergency treatment right away if you get any of the following signs of an allergic reaction: hives, chest tightness, wheezing, difficulty breathing, and/or swelling of the face.
  • Tell your healthcare provider about any side effect that bothers you or that does not go away.
  • Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) inside cells lining blood vessels in the choroid plexus, which makes the fluid that cushions the brain. The potential human implications of these animal tests are unknown.
     

Please click here for Prescribing Information.

Rebinyn® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.