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TAKE CONTROL OF HEMOPHILIA B

With Rebinyn®, you get more ways to take control—with simple dosing, flexible storage, and fast infusions.

Abdiel lives with hemophilia B and uses Rebinyn®

SIMPLIFIED FACTOR IX DOSING

Fixed dosing with Rebinyn® means your dose stays the same. No dosing adjustment needed—1 fixed dose for minor/moderate bleeds (40 IU/kg) and 1 fixed dose for major bleeds (80 IU/kg).a

rebinyn recommended dose
  • Follow your health care provider’s instructions regarding the dose and schedule for infusing Rebinyn®
  • Do not attempt to do an infusion yourself unless you have been taught how by your health care provider or hemophilia treatment center 

aA single dose should be enough for minor and moderate bleeds. Your doctor may recommend additional doses of 40 IU/kg.

WITH FLEXIBLE STORAGE, REBINYN® MAY FIT YOUR LIFESTYLE

Rebinyn® does not require refrigeration—so you can bring it with you when you’re on the go. Flexible storage means Rebinyn® can be stored at up to 86˚F, and it’s room temperature stable for up to 6 months, or up to 4 hours post-reconstitution. 

rebinyn no refrigeration required

bIf you choose to store Rebinyn® at room temperature, do not return it to the refrigerator. Rebinyn® vials can also be stored in the refrigerator at 36ºF-46ºF for up to 24 months until the expiration date stated on the label. Please see Prescribing Information for complete storage instructions.

QUICK TO PREPARE AND FAST TO INFUSE

If your time is important to you, then we have good news: Rebinyn® can be infused in as little as 1-4 minutes. And with our prefilled syringe, preparing a dose is quick, too.

With MixPro®, preparing a dose of Rebinyn® is as quick as:

Attachc

Prefilled diluent syringe contains 4 mL of diluent—works with any dose strength

Twistc

Adapter connects the syringe and vial

Mixc

After mixing, you can infuse Rebinyn®

cFor complete instructions on reconstitution and use, please refer to the Instructions for Use.

KEEPING TRACK IS QUICK, TOO

three rebinyn vials

Each vial comes with a peel-off label, which may help you track details about your infusions.

Rebinyn® can be infused in 1-4 minutes
how to prepare rebinyn dose

IT'S EASY TO GET STARTED

We'll show you step-by-step how to start treating with Rebinyn®.

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DO YOU PLAN ON TRAVELING?

With a Rebinyn® Travel Case, your factor will be ready when you are.

rebinyn travel case

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Selected Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.
     

Indications and Usage

What is Rebinyn®, Coagulation Factor IX (Recombinant), GlycoPEGylated?
Rebinyn® is an injectable medicine used to replace clotting Factor IX that is missing in patients with hemophilia B. Rebinyn® is used to treat, prevent, or reduce the frequency (number) of bleeding episodes in people with hemophilia B. Your healthcare provider may give you Rebinyn® when you have surgery. Rebinyn® is not used for immune tolerance therapy.

Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.

What should I tell my healthcare provider before using Rebinyn®?
Tell your healthcare provider if you:

  • have or have had any medical conditions.
  • take any medicines, including non-prescription medicines and dietary supplements.
  • are nursing, pregnant, or plan to become pregnant.
  • have been told you have inhibitors to Factor IX.

How should I use Rebinyn®?

  • Rebinyn® is given as an infusion into the vein.
  • Call your healthcare provider right away if your bleeding does not stop after taking Rebinyn®.
  • Do not stop using Rebinyn® without consulting your healthcare provider.

What are the possible side effects of Rebinyn®?

  • Common side effects include infusion site reaction (bruising, bleeding, swelling, pain, or redness), itching, and rash.
  • Your body can also make antibodies called “inhibitors” against Factor IX, including Rebinyn®, which may stop Rebinyn® from working properly. Your healthcare provider may need to test your blood for inhibitors from time to time.
  • Call your healthcare provider right away or get emergency treatment right away if you get, for example, any of the following signs of an allergic reaction: hives, chest tightness, wheezing, difficulty breathing, and/or swelling of the face.
  • You may be at an increased risk of forming blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider if you have chest pain, difficulty breathing, leg tenderness, or swelling.
  • Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) in certain cells in the brain. The potential human implications of these animal tests are unknown.
     

Please click here for Prescribing Information.

Rebinyn® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.