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Consider a treatment that lasts 5x longer.
When your phone has 5x the charge, it can last 5x longer—which could mean…



Consider a treatment that lasts 5x longer.
When your phone has 5x the charge, it can last 5x longer—which could mean…


So, what does 5x longer mean for your factor IX therapy?
Rebinyn® provides 5x longer half-life than BeneFIX®. "Half-life" is the time it takes for the level of factor in the blood to decrease by half (50%). A single dose of Rebinyn® decreases by half in 93 hours while BeneFIX decreases by half in 19 hours.a

aBased upon a phase 1 study comparing 25, 50, and 100 IU/kg doses of Rebinyn® to a 50 IU/kg dose of standard half-life rFIX in 7 adults and a 50 IU/kg dose of plasma-derived FIX in 8 adults. For Rebinyn®, estimated average FIX activity is adjusted to a dose of 50 IU/kg.
In another study, Rebinyn® achieved an 83-hour average half-life in adultsb
bBased upon a phase 3 study in 6 adults who received a single dose of Rebinyn® 40 IU/kg.
So, what does 5x longer mean for your factor IX therapy?
Rebinyn® provides 5x longer half-life than BeneFIX®. "Half-life" is the time it takes for the level of factor in the blood to decrease by half (50%). A single dose of Rebinyn® decreases by half in 93 hours while BeneFIX decreases by half in 19 hours.a

aBased upon a phase 1 study comparing 25, 50, and 100 IU/kg doses of Rebinyn® to a 50 IU/kg dose of standard half-life rFIX in 7 adults and a 50 IU/kg dose of plasma-derived FIX in 8 adults. For Rebinyn®, estimated average FIX activity is adjusted to a dose of 50 IU/kg.
In another study, Rebinyn® achieved an 83-hour average half-life in adultsb
bBased upon a phase 3 study in 6 adults who received a single dose of Rebinyn® 40 IU/kg.
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