GET EFFECTIVE PROTECTION IN SURGERY

In all major surgeries studied, doctors rated Rebinyn® as excellent or good in protecting their patients from bleeds. In fact, Rebinyn® provided 100% success rate in bleed control during surgery.a

aResults shown are from the surgery clinical study, which included 13 previously treated adolescent and adult patients. Patients received 1 infusion of Rebinyn® 80 IU/kg on the day of their surgeries. At the doctor’s discretion, patients received infusions of Rebinyn® 40 IU/kg for up to 3 weeks after surgery. Across 13 surgical procedures (9 major), the success rate in bleed control during surgery was evaluated on a four-point scale of excellent, good, moderate, or poor. Treatment success was defined as excellent or good bleed control.

Image of Clayton, who lives with hemophilia B, against a blue sky

All images of hemophilia B patients shown are for illustrative purposes only.

All images of hemophilia B patients shown are for illustrative purposes only.

THE POWER TO CONTROL BLEEDS WHEN THEY HAPPEN

THE POWER TO CONTROL BLEEDS WHEN THEY HAPPEN

Studies show that Rebinyn® provided effective on-demand bleed control.

RESOURCES FOR YOU

These materials can help you stay educated on bleeding disorders.

Educational resources for people with bleeding disorders

DESIGNED WITH SAFETY IN MIND

In clinical studies, Rebinyn® was shown to be safe and effective.

3 different Rebinyn® vials with peel off labels
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Selected Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.
     

Indications and Usage

What is Rebinyn® Coagulation Factor IX (Recombinant), GlycoPEGylated?
Rebinyn® is an injectable medicine used to replace clotting Factor IX that is missing in patients with hemophilia B. Rebinyn® is used to treat and control bleeding in people with hemophilia B. Your healthcare provider may give you Rebinyn® when you have surgery. Rebinyn® is not used for routine prophylaxis or for immune tolerance therapy.
 

Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.

What should I tell my healthcare provider before using Rebinyn®?
Tell your healthcare provider if you:

  • have or have had any medical conditions.
  • take any medicines, including non-prescription medicines and dietary supplements.
  • are nursing, pregnant, or plan to become pregnant.
  • have been told you have inhibitors to Factor IX.

How should I use Rebinyn®?

  • Rebinyn® is given as an infusion into the vein.
  • Call your healthcare provider right away if your bleeding does not stop after taking Rebinyn®.
  • Do not stop using Rebinyn® without consulting your healthcare provider.

What are the possible side effects of Rebinyn®?

  • Common side effects include swelling, pain, rash or redness at the location of the infusion, and itching.
  • Call your healthcare provider right away or get emergency treatment right away if you get any of the following signs of an allergic reaction: hives, chest tightness, wheezing, difficulty breathing, and/or swelling of the face.
  • Tell your healthcare provider about any side effect that bothers you or that does not go away.
  • Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) inside cells lining blood vessels in the choroid plexus, which makes the fluid that cushions the brain. The potential human implications of these animal tests are unknown.
     

Please click here for Prescribing Information.

Rebinyn® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.