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GET THE POWER TO CONTROL BLEEDS WHEN AND WHERE THEY HAPPENa

Studies show that Rebinyn® provided effective on-demand bleed control.

markus selfie hemophilia b

Image is for illustrative purposes only.

LOOKING FOR RELIABILITY IN YOUR FACTOR IX TREATMENT?

A study of adults and adolescents with hemophilia B showed that Rebinyn® treated 98% of bleeds with 1-2 infusions.b In the same study, bleed control was rated successful (defined as excellent or good) in 95% of 142 bleeding episodes.c

A study of adults and adolescents with hemophilia B showed that Rebinyn® treated 98% of bleeds with 1-2 infusions.b In the same study, bleed control was rated successful (defined as excellent or good) in 95% of 142 bleeding episodes.c

aRebinyn® should be stored between 36°F and 86°F.
bResults shown are from the on-demand arm of the adolescent/adult clinical study in previously treated patients. In this study, 15 people were treated for on-demand bleeds. In 14 people, there were a total of 143 bleeding episodes.
cResults shown are based on a bleed assessment by either the patient (for home treatment) or the study investigator (for treatment under medical supervision). Bleeds were assessed using a 4-point scale of excellent, good, moderate, or poor.

markus-hemophilia-surgery

Image is for illustrative purposes only.

Image is for illustrative purposes only.

PROTECTION IN SURGERY

PROTECTION IN SURGERY

Rebinyn® successfully protected patients from bleeds during all major and minor surgical procedures studied.

Rebinyn® successfully protected patients from bleeds during all major surgeries studied.

Learn About the Surgery Success Rate

KEEP IT SIMPLE

Rebinyn® offers simplified dosing and flexible storage.

dosing storage simple as 1 2 3

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HOW IT EXTENDS HALF-LIFE

Rebinyn® uses technology that helps factor stay in your body longer.

rebinyn extended half life

Learn How It Works

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Selected Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.
     

Indications and Usage

What is Rebinyn® Coagulation Factor IX (Recombinant), GlycoPEGylated?
Rebinyn® is an injectable medicine used to replace clotting Factor IX that is missing in patients with hemophilia B. Rebinyn® is used to treat and control bleeding in people with hemophilia B. Your healthcare provider may give you Rebinyn® when you have surgery. Rebinyn® is not used for routine prophylaxis or for immune tolerance therapy.
 

Important Safety Information

What is the most important information I need to know about Rebinyn®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.

Who should not use Rebinyn®?
Do not use Rebinyn® if you:

  • are allergic to Factor IX or any of the other ingredients of Rebinyn®.
  • are allergic to hamster proteins.

What should I tell my healthcare provider before using Rebinyn®?
Tell your healthcare provider if you:

  • have or have had any medical conditions.
  • take any medicines, including non-prescription medicines and dietary supplements.
  • are nursing, pregnant, or plan to become pregnant.
  • have been told you have inhibitors to Factor IX.

How should I use Rebinyn®?

  • Rebinyn® is given as an infusion into the vein.
  • Call your healthcare provider right away if your bleeding does not stop after taking Rebinyn®.
  • Do not stop using Rebinyn® without consulting your healthcare provider.

What are the possible side effects of Rebinyn®?

  • Common side effects include swelling, pain, rash or redness at the location of the infusion, and itching.
  • Call your healthcare provider right away or get emergency treatment right away if you get any of the following signs of an allergic reaction: hives, chest tightness, wheezing, difficulty breathing, and/or swelling of the face.
  • Tell your healthcare provider about any side effect that bothers you or that does not go away.
  • Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) inside cells lining blood vessels in the choroid plexus, which makes the fluid that cushions the brain. The potential human implications of these animal tests are unknown.
     

Please click here for Prescribing Information.

Rebinyn® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.