When you understand how the long-lasting formula of Rebinyn® can make a difference, you’ll be better equipped to manage your hemophilia B with confidence. This video breaks down the complexity of EHL Factor IX, so grab a towel because we’re headed to the beach!
HOW IT WORKS

Rebinyn® is an extended half-life treatment, which means it works in your body longer to control bleeds. The technology used to extend the half-life of Rebinyn® is called PEGylationa or “PEG” for short.
aPEG=polyethylene glycol.


HOW IT WORKS

Rebinyn® is an extended half-life treatment, which means it works in your body longer to control bleeds. The technology used to extend the half-life of Rebinyn® is called PEGylationa or “PEG” for short.
aPEG=polyethylene glycol.


THE POWER OF EXTENDED HALF-LIFE (EHL) FIX


WHAT IS HALF-LIFE?

Half-life is the time it takes for the level of factor in the blood to fall by half (50%).

HOW DOES PEGYLATION WORK?
HOW DOES PEGYLATION WORK?


The PEG molecule is designed to attach to a specific part of Rebinyn®

GlycoPEGylation keeps Rebinyn® in your blood longer to stop bleeding

Rebinyn® releases active FIX similar to human FIX
- Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) inside cells lining blood vessels in the choroid plexus, which makes the fluid that cushions the brain. The potential human implications of these animal tests are unknown
QUESTIONS ABOUT ON-DEMAND TREATMENT?


Image is for illustrative purposes only.
Image is for illustrative purposes only.
QUESTIONS ABOUT ON-DEMAND TREATMENT?

Rebinyn® is an on-demand therapy, which means you only take it when bleeds occur. Most bleeds are treated with 1-2 infusions. Treating on-demand means there’s no need to keep to a strict dosing schedule. Rebinyn® is not intended for routine prophylaxis.
For people living with mild, moderate, or severe hemophilia B, the higher factor levels achieved and sustained with Rebinyn® may allow for fewer infusions.b Talk to your doctor to explore whether Rebinyn® is right for you and your lifestyle.
bBased upon treatment guidelines for factor activity levels for different severities of bleeding.

DESIGNED WITH SAFETY IN MIND
In clinical studies, Rebinyn® was shown to be safe and effective.


RESOURCES FOR YOU
These materials can help you stay educated on bleeding disorders.
